Complex Conditions Tricuspid Regurgitation - Severe Lesson Waveform Anatomy play pause Table of Contents 1Mitral Regurgitation - Severe 2Tricuspid Regurgitation - Severe 3Mitral Stenosis Severe and Regurgitation Mild - Rheumatic Origin 4Aortic Stenosis Moderate and Regurgitation Mild - Rheumatic Origin 5Mitral Regurgitation and Aortic Regurgitation 6Acute Pericarditis Practice Quiz This video is an animation of Tricuspid Regurgitation - Severe A#28 (lesson# 2) within course number 2. This is an example of severe tricuspid regurgitation which is caused by degeneration of the tricuspid valve leaflets.The first heart sound is normal. The second heart sound is unsplit.There is a loud, rectangular, pansystolic murmur. There is a brief, rumbling, diamond-shaped diastolic murmur.In the anatomy tab you can see the enlarged right atrium and right ventricle. You can see the turbulent blood flow from the right ventricle into the right atrium. This is the systolic murmur. You can see the brief turbulent blood flow from the right atrium to the right ventricle in diastole. This is caused by too much blood in the right atrium which forces blood back into the ventricle during diastole producing the flow rumble.To differentiate tricuspid regurgitation from mitral regurgitation, the maximum intensity of the tricuspid murmur is heard at the left lower sternal border. In addition, the murmur intensity increases with inspiration.