Cardiac Conditions Associated with Sudden Death Mitral Valve Prolapse (Click with Late Systolic Murmur) Lesson Waveform Anatomy play pause Table of Contents 1Hypertrophic Cardiomyopathy 2Aortic Stenosis - Severe 2 3Arrhythmogenic RV Dysplasia 4Mitral Valve Prolapse (Click with Late Systolic Murmur) 5Myocarditis 6Commotio Cordis 7Ebstein's Anomaly Practice Quiz This video is an animation of Mitral Valve Prolapse (Click with Late Systolic Murmur) A#30 (lesson# 4) within course number 4. There is a medium pitched diamond shaped murmur which begins right after a mid systolic click and runs to the end of systole.The intensity of the murmur increases and its starting point begins earlier in systole as left ventricular volume decreases (going from supine to standing). The intensity of the murmur and its starting position move later in systole as the volume increases (by raising the legs while in the supine position). The mid-systolic click also moves in tandem with the murmur. On the anatomy tab you can see that the murmur is caused by the prolapse of the posterior mitral valve leaflet. The murmur is represented by turbulent flow from the left ventricle into the left atrium.